| Stage 12: Tonnerre to Vittel, 211.5 km |
| 1 Nicki Sörensen (Den) Team Saxo Bank |
4:52:24 |
| 2 Laurent Lefevre (Fra) BBOX Bouygues Telecom |
at 0:48 |
| 3 Franco Pellizotti (Ita) Liquigas |
| 4 Marcus Fothen (Ger) Team Milram |
| 5 Egoi Martinez (Esp) Euskaltel - Euskadi |
| 6 Sylvain Calzati (Fra) Agritubel |
all s.t. |
| 7 Rémi Pauriol (Fra) Cofidis, Le Credit en Ligne |
1:33 |
| 8 Mark Cavendish (GBr) Team Columbia - High Road |
5:58 |
| 9 Thor Hushovd (Nor) Cervelo Test Team |
| 10 Marco Bandiera (Ita) Lampre - NGC |
| |
| 16 Lance Armstrong (USA) Astana |
| 21 Alberto Contador (Esp) Astana |
| 48 Rinaldo Nocentini (Ita) AG2R La Mondiale |
| 148 Ryder Hesjedal (Can) Garmin - Slipstream |
all s.t. |
| |
| GC |
| 1 Rinaldo Nocentini (Ita) AG2R La Mondiale |
48:27:21 |
| 2 Alberto Contador (Esp) Astana |
at 0:06 |
| 3 Lance Armstrong (USA) Astana |
0:08 |
| 4 Levi Leipheimer (USA) Astana |
0:39 |
| 5 Bradley Wiggins (GBr) Garmin - Slipstream |
0:46 |
| |
| 69 Ryder Hesjedal (Can) Garmin - Slipstream |
32:02 |
