| Stage 4: Cambrai to Reims, 153.5 km |
| 1 Alessandro Petacchi (Ita) Lampre-Farnese Vini |
3:34:55 |
| 2 Julian Dean (NZl) Garmin - Transitions |
| 3 Edvald Boasson Hagen (Nor) Team Sky |
| 4 Robbie McEwen (Aus) Team Katusha |
| 5 Robert Hunter (RSA) Garmin - Transitions |
| 6 Sébastien Turgot (Fra) Bbox Bouygues Telecom |
| 7 Jose Joaquin Rojas (Esp) Caisse d'Epargne |
| 8 Daniel Oss (Ita) Liquigas-Doimo |
| 9 Thor Hushovd (Nor) Cervelo Test Team |
| 10 Oscar Freire Gomez (Esp) Rabobank |
| |
| 42 Michael Barry (Can) Team Sky |
| 95 Ryder Hesjedal (Can) Garmin - Transitions |
all s.t. |
| |
| GC |
| 1 Fabian Cancellara (Sui) Team Saxo Bank |
18:28:55 |
| 2 Geraint Thomas (GBr) Team Sky |
at 0:23 |
| 3 Cadel Evans (Aus) BMC Racing Team |
0:39 |
| 4 Ryder Hesjedal (Can) Garmin - Transitions |
0:46 |
| 5 Sylvain Chavanel (Fra) Quick Step |
1:01 |
| 6 Andy Schleck (Lux) Team Saxo Bank |
1:09 |
| 7 Thor Hushovd (Nor) Cervelo Test Team |
1:19 |
| 8 Alexandre Vinokourov (Kaz) Astana |
1:31 |
| 9 Alberto Contador (Esp) Astana |
1:40 |
| 10 Jurgen Van Den Broeck (Bel) Omega Pharma-Lotto |
1:42 |
| |
| 18 Lance Armstrong (USA) Team Radioshack |
2:30 |
| 61 Michael Barry (Can) Team Sky |
3:33 |
