Novi Ligure to Lagnasco 184 km
| 1 Philippe Gilbert (Bel) Silence - Lotto | 4:32:54 |
| 2 Daniel Moreno Fernandez (Esp) Caisse d\'Epargne | |
| 3 Francesco Gavazzi (Ita) Lampre - N.G.C. | |
| 4 Luca Paolini (Ita) Acqua & Sapone - Caffe Mokambo | all s.t. |
| 5 Reinier Honig (Ned) Vacansoleil Pro Cycling Team | at 0:02 |
| 6 Paul Martens (Ger) Rabobank | s.t. |
| 7 Alexandre Usov (Blr) Cofidis, Le Credit en Ligne | 0:04 |
| 8 Gerben Löwik (Ned) Vacansoleil Pro Cycling Team | |
| 9 Dries Devenyns (Bel) Quick Step | |
| 10 Pablo Lastras Garcia (Esp) Caisse d\'Epargne | |
| 11 Alessandro Ballan (Ita) Lampre - N.G.C. | |
| 12 Nicolas Roche (Irl) AG2R La Mondiale | |
| 13 Santo Anza\' (Ita) ISD | |
| 14 Nico Sijmens (Bel) Cofidis, Le Credit en Ligne | |
| 15 Enrico Gasparotto (Ita) Lampre - N.G.C. | |
| 16 Alexandre Botcharov (Rus) Team Katusha | |
| 17 Bauke Mollema (Ned) Rabobank | |
| 18 Nikita Eskov (Rus) Team Katusha | |
| 19 Maxime Monfort (Bel) Team Columbia - HTC | |
| 20 Aitor Hernandez Gutierrez (Esp) Euskaltel - Euskadi | all s.t. |
| 52 Christian Meier (Can) Garmin - Slipstream | 0:19 |
| 58 Michael Barry (Can) Team Columbia - HTC | 0:34 |
